After reuniting Sylar (Zachary Quinto) and Elle (guest star Kristen Bell), Arthur (guest star Robert Forster) orders them to find Claire (Hayden Panettiere) and bring her to him. Matt (Greg Grunberg), Hiro (Masi Oka) and Ando (James Kyson Lee) team up together and follow Daphne (guest star Brea Grant) to her hometown of Lawrence, Kansas to discover what she's been hiding. Meanwhile, Nathan and Peter Petrelli (Adrian Pasdar and Milo Ventimiglia) travel together to Haiti in search of the only man that can stop their father from destroying the world, the Haitian (Jimmy Jean-Louis). Jack Coleman and Ali Larter also star. Robert Forster also guest stars.

To prepare for the confrontation ahead, Hiro (Masi Oka) follows respected businessman, husband and father Arthur Petrelli (guest star Robert Forster) in the days before he "died" -- to discover what drove him to create rival company Pinehearst and strike at Angela (Cristine Rose). Later, a moment unfolds where Sylar (Zachary Quinto), horrified and guilt-ridden, might have stopped his murderous pursuit of abilities -- that is, if H.R.G. (Jack Coleman) and Elle (guest star Kristen  Bell) had swayed from their monstrous assignment. Finally, under the wing of Company man Thompson (guest star Eric Roberts) agent-in-training Meredith (guest star Jessalyn Gelsig) watches her new life go up in smoke, following the arrival of her hot-headed brother. Greg Grunberg, James Kyson Lee, Ali Larter, Hayden Panettiere, Adrian Pasdar, Sendhil Ramamurthy, Dania Ramirez and Milo Ventimiglia also star. Jimmy Jean-Louis, Malcolm McDowell, Ntare Guma Mbaho Mwine, Ron Perkins, Blake Shields, and Jeff Staron guest star.

Impressed by his sudden ruthlessness, Villains Knox (guest star Jamie Hector) and Daphne (guest star Brea Grant) bring Hiro (Masi Oka) -- among others -- into the Pinehearst fold, and give him an assignment. With Angela (Cristine Rose) and the Company paralyzed by recent events, Peter (Milo Ventimiglia) goes directly to Pinehearst for answers, and irrevocably changed by the shocking meeting. Meanwhile, Claire (Hayden Panettiere) and her mother Sandra (Ashley Crow) attempt to free Meredith (Jessalyn Gilsig) from the thrall of escaped Villain Doyle (David H. Lawrence XVII), who has the ability to take mental and physical control of others. Later, Nathan (Adrian Pasdar) brings Tracy (Ali Larter) to Suresh (Sendhil Ramamurthy), hoping he can shed light on the surprising origin of their abilities. Jack Coleman, Greg Grunberg, James Kyson Lee, Zachary Quinto and Dania Ramirez star. David Anders, Alan Blumenfeld, Robert Forster and Blake Shields guest star.

Seeing a future where nearly everyone has abilities, a world destined for destruction, Peter resolves to prevent this earth-shattering end -- whatever the cost -- and so takes on a dark, unwieldy ability to save the world -- gambling (wrong) that it won't destroy him and everything he loves first. After allowing Angela's (Cristine Rose) half of "the formula" to be stolen, Hiro (Masi Oka) and Ando (James Kyson Lee) set out to uncover the identity of the Villain who hired Daphne (guest star Brea Grant) - and must consult with the person who knows these rogues best...Adam Monroe (guest star David Anders). After the bloodbath at the bank, H.R.G. (Jack Coleman) resolves to get rid of his new partner. Meanwhile, determined to be a hero, Claire (Hayden Panettiere) hits the road after one of the Villains from H.R.G.'s old files. Suresh (Sendhil Ramamurthy) gives in to impulse. Linderman (guest star Malcolm McDowell) and Molly (guest star Adair Tishler) return in unexpected manners. A new romance ignites between two Heroes. Ali Larter, Adrian Pasdar, Greg Grunberg, Zachary Quinto and Dania Ramirez star. Randall Bentley, Ashley Crow, Jessalyn Gilsig, Ronald Guttman, Jamie Hector, Jimmy Jean-Louis, Ntare Mwine and Thomas Robinson guest star.